How to diagnose and treat
carpal tunnel syndrome

Diagnosis & treatment of carpal tunnel syndrome

Most of the time, diagnosis starts with your story. A clinician will ask where you feel tingling or numbness, when it happens (often at night or with activities like driving or typing), and how it is affecting your sleep, grip, and daily tasks.¹ ²

They will also ask about things that can raise risk or change the plan, like pregnancy, diabetes, thyroid disease, inflammatory arthritis, and past wrist injuries.¹ ²

How do clinicians diagnose carpal tunnel syndrome?

During the exam, clinicians usually check:

  • Which fingers feel numb or tingly, and whether symptoms match the median nerve pattern.¹ ²
  • Strength and coordination, especially pinch strength and thumb control. Weakness or visible thinning at the base of the thumb can suggest a more advanced case.¹ ²
  • Simple wrist tests that try to reproduce symptoms (for example, bending the wrist or gently tapping over the nerve). These tests can support the diagnosis, but they are not perfect on their own.¹ ²

When are nerve tests or ultrasound used?

Carpal tunnel syndrome is often diagnosed clinically, but testing can be helpful in specific situations.¹ ³Clinicians may recommend nerve conduction studies, sometimes paired with needle electromyography, when:

  • the diagnosis is unclear or symptoms are atypical
  • symptoms are severe, constant, or progressing
  • there is weakness or muscle wasting
  • surgery is being considered, or documentation is needed for work-related cases¹³

Some clinicians also use ultrasound to look at the median nerve and nearby structures, especially if they suspect a structural cause or want additional confirmation.¹

What are the treatment options for carpal tunnel syndrome?

Treatment is usually chosen based on how intense symptoms are, how long they have been present, and whether there are signs of nerve damage. Many people start with conservative care, and surgery is typically reserved for cases that do not improve enough or show more serious nerve involvement.¹²

Education and early activity

Common first steps include reducing positions and tasks that repeatedly aggravate symptoms, and finding more neutral wrist setups for sleep and daily activities.¹²

Night splinting

A neutral-position wrist splint worn at night is a common starting option for mild to moderate symptoms. Evidence supports splinting compared with no treatment, and it is generally safe and low-cost.⁴

Corticosteroid injection

A single corticosteroid injection can improve symptoms faster than splinting for many people in the short term. In a large primary-care trial, injection provided better symptom relief at around 6 weeks than a night splint.⁵Longer-term follow-up suggests that symptom differences tend to narrow over time, and many people still consider surgery later depending on how symptoms evolve.⁶

Exercise-based rehabilitation

Exercise-based care, including guided movement and strengthening, is often used alongside splinting and activity changes. Some people also use nerve and tendon gliding exercises as part of a broader plan. Evidence varies across approaches, so these are typically used as supportive options rather than stand-alone fixes for more severe compression.¹²

Surgery

Carpal tunnel release is usually considered when:

  • symptoms remain function-limiting after a trial of high-quality non-surgical care
  • there is thumb weakness or thenar muscle wasting
  • nerve testing shows more severe changes, or symptoms are rapidly worsening¹²³

Both open and endoscopic approaches can work well, with broadly similar long-term outcomes. Some evidence suggests faster early recovery with endoscopic techniques, while open surgery is widely available and effective.⁷

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How can I find pain relief for whiplash?

If your symptoms are mild or come and go, these low-risk strategies often help people feel more in control:

  • Protect your sleep: Try a neutral wrist position at night. If you tend to curl your wrists, a night splint can help hold a more comfortable position.⁴
  • Use pacing for hand-heavy tasks: Break long activities (typing, tools, hobbies) into shorter blocks with brief rests.¹²
  • Reduce sustained gripping: Use larger grips when possible, and switch hands or change positions more often.¹²
  • Pay attention to “warning signs”: If numbness becomes constant, thumb strength is clearly dropping, or symptoms rapidly worsen after an injury, get medical review promptly.¹²

If a new activity makes you sore but the pain settles within a day and doesn’t keep worsening, that’s usually a safe level of challenge.

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Footnotes

1

NICE Clinical Knowledge Summary. Carpal tunnel syndrome: assessment and management. 2024–2025.

2

BMJ Best Practice. Carpal tunnel syndrome. Updated 2025.

3

American Academy of Orthopaedic Surgeons (AAOS). Updated Clinical Practice Guideline for the management of carpal tunnel syndrome. 2024.

4

Zivkovic S, et al. Quality measures in electrodiagnosis: carpal tunnel syndrome. Muscle Nerve. 2020.

5

Salimi M, et al. Diagnostic accuracy of ultrasonography for carpal tunnel syndrome. Clin Neurol Neurosurg. 2024.

6

Expert consensus on combined electrodiagnostic testing and neuromuscular ultrasound in carpal tunnel syndrome. Clin Neurophysiol. 2022.

7

Rosenfeld M, et al.; Crawford JR, et al. Early active mobilization versus collar in acute whiplash: randomized trials. Emerg Med J. 2004 and related series.

8

Chesterton LS, et al. Corticosteroid injection versus night splinting for mild to moderate carpal tunnel syndrome (INSTinCTS RCT). Lancet. 2018.

9

Chesterton LS, et al. Long term outcomes of injection versus splinting for carpal tunnel syndrome: 24 month extension of INSTinCTS. Rheumatology. 2022–2023.

10

Page MJ, et al. Splinting for carpal tunnel syndrome. Cochrane Database Syst Rev. 2023 update.

11

Lusa V, et al. Surgical versus non surgical treatment for carpal tunnel syndrome. Cochrane Database Syst Rev. 2023.

12

University of Queensland RECOVER Injury Research Centre. WhipPredict clinical prediction rule and patient booklet. 2018.

13

Malik AT, et al. Outcomes and cost of endoscopic versus open carpal tunnel release in a large database. World Neurosurg. 2022.

14

PLOS ONE. Diabetes and carpal tunnel syndrome: systematic review and meta analysis. 2024.

15

van den Berge M, et al. Physical and psychosocial work exposures and incident carpal tunnel syndrome: systematic review. Ann Work Environ Health. 2023.

16

The Lancet. Carpal tunnel syndrome: new evidence for common practices. 2025 clinical update commentary.

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