AI Care

Psychological predictors for chronic MSK pain

Fabiola Costa

Study overview

Psychological factors can shape how people experience pain and respond to rehabilitation. This study evaluated whether baseline depression, anxiety, and fear-avoidance beliefs helped predict pain outcomes after fully remote digital MSK care.

The analysis used a large real-world sample of approximately 4,700 members across all 50 states. Researchers used advanced modeling, including structural equation modeling, to evaluate associations between psychological factors and pain outcomes.

Key findings

Depression and fear avoidance helped predict pain outcomes

The Sword summary reports that depression and fear-avoidance factors helped predict pain outcomes in digital MSK care.

The study used a large real-world sample

The analysis included approximately 4,700 members across all 50 states, giving the study a broad real-world data foundation.

Robust modeling strengthened the analysis

The study used advanced modeling to reduce common analytic bias and tested outcomes in multiple ways to assess robustness.

The findings support more personalized care

Understanding psychological predictors may help care teams identify members who need additional support, earlier intervention, or more tailored care pathways.

Why this study matters

This study is important because it helps explain why some members recover differently from others. It supports a more precise model of digital MSK care, where baseline psychological factors can inform expectations and treatment strategy.

The page should emphasize clinical science rather than algorithmic novelty alone. The strongest message is that mental health and fear avoidance are not side issues in MSK care. They are meaningful predictors that should inform how care is delivered.

Read the full study


Footnotes

  1. 1

    Janela D, Tong X, Pires D, Fonseca H, Pereira AP, Dias Correia F, Costa F. Psychological Predictors of Pain Outcomes After Fully Remote Digital Rehabilitation for Chronic Musculoskeletal Pain. PAIN Reports. 2026.

Portugal 2020Norte 2020European UnionPlano de Recuperação e ResiliênciaRepública PortuguesaNext Generation EU